Dorzolamide inter-9

Dorzolamide inter-9 - Names and Identifiers

Name	(4S)-4-Acetamide-5,6-Dihydro-6-Methyl-2-Sulfonamide-Thio[2,3-B]Thiopyran7,7Dioxide
Synonyms	Dorzolamide inter-9 Dorzolamide hydrochloride ninth step (4S-trans)-N-[2-(aminosulfonyl)-5,6-dihydro-6-methyl-7, N-[(4S,6S)-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b] (4S)-4-Acetamide-5,6-Dihydro-6-Methyl-2-Sulfonamide-Thio[2,3-B]Thiopyran7,7Dioxide N-[(4S,6S)-6-METHYL-7,7-DIOXO-2-SULFAMOYL-5,6-DIHYDRO-4H-THIENO[2,3-B]THIOPYRAN-4-YL]ACETAMIDE N-((4S,6S)-6-Methyl-7,7-dioxido-2-sulfaMoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetaMide N-[(4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide (4S-trans)-N-[2-(aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno-[2,3-b]thiopyran-4-yl]-Acetamid (4S-TRANS)-N-[2-(AMINOSULFONYL)-5,6-DIHYDRO-6-METHYL-7,7-DIOXIDE-4H-THIENO-[2,3-B]THIOPYRAN-4-YL]-ACETAMIDE (4S-trans)-N-[2-(aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno-[2,3-b] thiopyran-4-yl]-acetamide N-((4S,6S)-6-Methyl-7,7-Dioxo-2-Sulfamoyl-4,5,6,7-Tetrahydro-7Lambda6-Thieno[2,3-B]Thiopyran-4-Yl)-Acetamide Acetamide,N-[2-(aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno-[2,3-b] thiopyran-4-yl]-,(4S-trans)-
CAS	147200-03-1
InChI	InChI=1/C10H14N2O5S3/c1-5-3-8(12-6(2)13)7-4-9(20(11,16)17)18-10(7)19(5,14)15/h4-5,8H,3H2,1-2H3,(H,12,13)(H2,11,16,17)/t5-,8-/m0/s1

Dorzolamide inter-9 - Physico-chemical Properties

Molecular Formula	C10H14N2O5S3
Molar Mass	338.42
Density	1.62
pKa	9.38±0.60(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.647

Dorzolamide inter-9 - Introduction

(4S)-4-Acetamide-5, [2,3-b] Thiopyran7,7dioxide, often abbreviated as MTSEA or MTSEA-ac. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White to light yellow solid
-molecular formula: C12H15NO4S2
-Molecular weight: 313.39g/mol
-Melting Point: 140-142 ° C
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol, ethanol, etc.

Use:
- MTSEA is mainly used as a strong oxidant and electron accepting body.
-It is often used in biochemical research to modify cysteine residues in proteins or nucleic acids.
Derivatives of-MTSEA can be used to generate compounds for studying ion channel and receptor functions.

Method:
- MTSEA-ac can be prepared by the reaction of MTSEA and acetic anhydride.

Safety Information:
-The MTSEA-ac should be used in a laboratory environment with appropriate precautions, including gloves, glasses, and an exhaust system outside the laboratory.
-It may irritate the skin, eyes and respiratory tract, so direct contact should be avoided when using.
-Care should be taken to avoid contact with oxidizing substances when storing and carrying MTSEA-ac.
-Detailed safety operation information can be obtained in the relevant chemical safety data sheet (MSDS).

Last Update：2024-04-10 22:29:15